TRT clinics in South Dakota
13 clinics across 3 cities.
South Dakota has 13 testosterone replacement therapy clinics located throughout the state, with the highest concentration in Sioux Falls, Dakota Dunes, and Rapid City. Gameday Men's Health operates multiple locations in the state as a multi-location provider. These clinics offer testosterone replacement therapy and men's health services.
- Clinics
- 13
- Cities
- 3
- Avg. rating
- 4.8★
State highlights
Largest TRT clinic markets in South Dakota
Browse all clinics in a city by selecting one of the market cards below.
Top-rated TRT clinics in South Dakota
The top 10 clinics statewide by public rating and review volume. Ratings are public Google review references, not first-party reviews or a measure of medical quality. Confirm services and licensing with each clinic before booking.
| Clinic | City | Rating | Reviews | Services | Contact |
|---|---|---|---|---|---|
| Trillion Health and Hormone Clinic | Sioux Falls | 4.9 ★ | 138 | TRT | Call·Site |
| Gameday Men's Health Sioux Falls, SD | Sioux Falls | 5.0 ★ | 118 | TRT | Call·Site |
| Gameday Men's Health Rapid City, SD | Rapid City | 5.0 ★ | 101 | TRT | Call·Site |
| Gameday Men's Health Dakota Dunes, SD | Dakota Dunes | 5.0 ★ | 79 | TRT | Call·Site |
| Limitless Male Medical Clinic | Sioux Falls | 4.5 ★ | 102 | TRT | Call·Site |
| Accelerate Wellness - Longevity Medicine Clinic | Sioux Falls | 4.8 ★ | 46 | Wellness | Call·Site |
| Limitless Male Medical Clinic | Dakota Dunes | 4.7 ★ | 47 | TRT | Call·Site |
| Well Beyond Functional Medicine | Rapid City | 4.8 ★ | 24 | Wellness | Call·Site |
| Radiant Health and Hormone Therapy | Sioux Falls | 5.0 ★ | 10 | Wellness | Call·Site |
| Hormones Gone Wild | Sioux Falls | 5.0 ★ | 9 | TRT | Call·Site |
TRT clinic selection checklist
- Confirm the clinic requires baseline labs before prescribing.
- Ask how often they monitor testosterone, hematocrit, PSA, and estradiol.
- Compare all-in monthly cost, lab fees, refill policies, and contract terms.
Compare telehealth TRT options
If the closest South Dakota clinic is inconvenient, see online TRT providers with published SD coverage.
Guide to TRT costs
Understand consult fees, lab costs, medications, insurance, and cash-pay pricing before booking.
Clinic owners
Own or manage a TRT clinic in South Dakota?
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TRT clinic FAQ for South Dakota
How many TRT clinics are in South Dakota?
TRT Index lists 13 testosterone and hormone therapy clinics across 3 cities in South Dakota. Listings are compiled from public sources; verify services and availability directly with each clinic.
Which South Dakota cities have the most TRT clinics?
The largest markets in our directory are Sioux Falls (9 clinics). Use the city pages to compare providers locally.
Can I get TRT online in South Dakota?
Yes. Several telehealth providers prescribe testosterone to patients in states where their clinicians are licensed, ship labs to your door, and mail medication. Compare them on our ranked list of the best online TRT clinics before choosing between local and remote care.
Medical disclaimer: TRT Index is for general information only and is not medical advice, diagnosis, or treatment. Discuss symptoms, lab results, risks, and treatment decisions with a licensed clinician.
All TRT clinic cities in South Dakota
TRT clinics in smaller South Dakota cities
Cities with one or two clinics are listed here in full. Larger cities have their own page above.
Dakota Dunes, SD
- Gameday Men's Health Dakota Dunes, SD★ 5.0 (79) · (605) 540-4050
- Limitless Male Medical Clinic★ 4.7 (47) · (605) 273-3399
Rapid City, SD
- Gameday Men's Health Rapid City, SD★ 5.0 (101) · (605) 204-6757
- Well Beyond Functional Medicine★ 4.8 (24) · (605) 219-9525